CSF, is an abbreviation for
Cerebrospinal Fluid, is an essential component of the brain and the central
nervous system. Produced by the choroid plexus (Lower arterial part) of the
brain, the CSF not only acts as a protection mechanism, but also as a chemical
stabilizer, brain buoyancy regulator, toxin clearance system, and pressure
maintenance system. It is produced daily and circulated throughout the exterior
of the brain (subarachnoid space), such that only 100-160ml is circulated at
any given time. The relevance of CSF therefore lies in the diseases that can
cause any disruptions in the functionality of the CSF and thereby the function
of the brain. This is therefore a growing area of interest, as research is
still in process to understand the dynamics of CSF production, regulation and
the blood-brain-barrier.
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One of the accepted ways to diagnose
the condition and the contents of CSF is by Lumbar puncture. Lumbar puncture
(LP) is done at the lower spine region called as lumbar, a surgeon/ doctor/
physician first sterilizes the area and then injects a needle which collects
the CSF in a vial. CSF of a healthy individual is usually clear in visibility
and water like in composition. Murky or whitish fluid is a sign of infection,
generally meningitis, etc. Some scientists believe there exists a relation
between Alzheimer’s disease and CSF content, the presence of certain proteins
indicates the existence or the possibility for the condition. Besides this, CSF
is also used as a route for administration of any drugs in adverse cases or
complications, although the risk of increasing cranial pressure is high. CSF is
under the radar for many neurotropic and psychedelic drug manufacturers,
besides those tending to brain stroke/hemorrhage and neurogenerative disorders.
CSF shunt is another area of concern/interest; these shunts are regions where
there is passage of the CSF from one region to the other.
Shunt drains are certain type of
devices that help in decreasing the cranial pressure during surgeries and other
procedures that may require its assistance, e.g. tumor removal, infection
therapy (antibiotics) and hematoma to name a few . Lumbar puncture is nowadays
almost extensively used for any differential diagnostic procedures.
Hydrocephalus is a majorly diagnosed condition, generally associated with
increased cranial pressure.
One of the major factors driving the
CSF management market includes the fact that the growing geriatric population
in the world shall present a significant market in the coming years. Also the
population explosion shall mean that there would be a greater number of
individuals having the symptoms of Alzheimer’s and Parkinson’s, to name a few.
Patients also prefer minimally invasive surgical procedure hence they are
inclined to favor the technology. The factors opposing the growth of CSF market
would be the growing concern for the CSF management, the restraints in clinical
trials for the development of designs and the high price of the devices.
At present the largest market for
CSF devices and procedures remains with the North Americas, this is followed by
the European region. The Asia-Pacific region sees the highest growth potential
and is expected to displace the European market soon, then after, the North
American market. The Asian region has the highest population and hence has the
greatest potential. The entry of Asian Players on the global scale shall also
prove to be a valuable stimulant to the overall global market. The rest of the
world region has Brazil and the Middle-East as its prime market. Africa
currently is the smallest market by volume.
Some of the company’s manufacturing
devices related to CSF are, Medtronic Becker, Codman EDS, Integra LifeSciences
and Liquogaurd Moeller to name a few.
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This research report analyzes this
market depending on its market segments, major geographies, and current market
trends. Geographies analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
This report provides comprehensive
analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming years
This report is a complete study of
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provides market projections for the coming years. It includes analysis of
recent developments in technology, Porter’s five force model analysis and
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entrants along with detailed value chain analysis.
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