Lifestyle choices of the present generation have changed drastically from the previous one, spurring severe consequences and health hazards. Increasing cases of cancer registered around the world is one such consequence that is raising alarm globally. Of the various kinds of cancer, colorectal cancer is among the more common ones.This type of cancer is identified by abnormal cell growth in the inner walls of the large intestine. Many a time, hereditary factors play a very important role in determining the chances of a person developing colorectal cancer. It is a fatal disease, owing to which a majority of the research is dedicated to discovering drugs to cease the abnormal cell growth to increase the patient’s lifespan. Apart from lifestyle choices, the common tendency among people to postpone tests, diagnosis, and subsequent treatment is the key factor responsible for the increasing number of patients diagnosed with colorectal cancer every year.
Colorectal Cancer Drugs to Register High Demand Owing to Low Severity of Side-Effects
Cancer researchers of modern times are more aware about the genetic changes that occur at the onset of this fatal disease. As a result, the drugs and treatment procedures that researchers and scientists are coming up with these days focus more on addressing such fundamental causes rather than the easily visible symptoms of the disease. These drugs and treatment procedures fall within the ambit of the colorectal cancer therapeutics market.
When compared to other standard drugs administered during chemotherapy, drugs used for the treatment of colorectal cancer work in a completely different way. One of the major benefits of colorectal cancer drugs is that they have different, less intense side effects than drugs used for other cancers. These drugs can be either administered to the patients independently or in combination with other drugs.
CYRAMZA, CPP-1X, Xilonix, MelCancerVac, Lonsurf, TS-1/Teysuno, and Nintedanib are the most common drugs used in colorectal cancer therapeutics.
Global Colorectal Cancer Therapeutics Market Report
Impressive Healthcare Facilities makes North America the Largest Regional Colorectal Cancer Therapeutics Market
Geographically, the market for colorectal cancer therapeutics can be segmented into Europe, Asia Pacific, North America, and Rest of the World. Of these, North America leads the global colorectal cancer therapeutics market, owing to the greater number of colorectal cancer cases registered in the region. In addition, the overall healthcare facility scenario in North America is highly developed. It has adequate infrastructure and the population is aware of the treatment and diagnosis options for colorectal cancer, which has positively impacted the colorectal cancer therapeutics market in the region. Fluorouracil and Capecitabine are two of the most commonly used chemotherapy drugs in North America used during the treatment of colorectal cancer.
Asia Pacific is expected to emerge as the fastest growing regional market for colorectal cancer therapeutics in the next few years. Escalating population density together with rising incidence of colorectal cancer in China and India is likely to drive the colorectal cancer therapeutics market in the region. However, unwillingness of the regional population to adopt the new school of drugs and inadequate awareness pertaining to the treatment and diagnosis of the fatal disease will inhibit the colorectal cancer therapeutics market growth in the region to an extent.
Of the leading companies in the global colorectal cancer therapeutics market, Pfizer and Eli Lilly have recently collaborated to continue clinical research on Tanezumab (a drug used as cancer painkiller). To continue its research on the drugs, Pfizer is likely to receive US$200 million from Eli Lilly. Other prominent names in the market are Bayer Healthcare Pharmaceuticals, Taiho Pharmaceutical, and Boehringer Ingelheim.
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 Colorectal Cancer
2.2 Symptoms
2.3 Epidemiology
2.4 Pathophysiology
2.4.1 Histology
2.4.2 Genetic Basis
2.4.3 Etiology of Colorectal Cancer
2.5 Diagnosis
2.5.1 Digital Rectal Examination
2.5.2 Fecal Occult Blood Test
2.5.3 Flexible Sigmoidoscopy
2.5.4 Colonoscopy
2.5.5 Virtual Colonoscopy
2.5.6 Double Contrast Barium Enema
2.6 Prognosis and Disease Staging
2.7 Treatment Options
2.7.1 Surgery and Radiation Therapy
2.7.2 Chemotherapy
2.7.3 Targeted Therapies
2.7.4 Resistance to Pharmacological Therapies
2.7.5 Treatment Guidelines
2.8 MRRSE Research Report Guidance
3 Marketed Products
3.1 Key Marketed Products
3.1.1 Immunotherapies
3.1.2 Targeted Therapies
3.1.3 Hyperthermic Intraperitoneal Chemotherapy
3.2 Heat Map for Marketed Products
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4 Pipeline Analysis
4.1 Overall Pipeline
4.2 Pipeline Analysis by Molecule Type
4.3 Pipeline Analysis by Mechanism of Action
4.4 Clinical Trials
4.5 Failure Rate
4.6 Clinical Trial Size
4.7 Duration
4.8 Promising Drug Candidates in Pipeline
4.8.1 Lonsurf (TAS-102 (tipiracil + trifluridine)) – Taiho Pharmaceutical
4.8.2 Cyramza – ramucirumab – Eli Lilly and Company
4.8.3 TS-1/Teysuno (tegafur + gimeracil + oteracil) – Taiho Pharmaceutical
4.8.4 CPP-1X (eflornithine hydrochloride) + sulindac – Cancer Prevention Pharmaceuticals
4.8.5 MelCancerVac – DanDrit Biotech
4.8.6 Xilonix – XBiotech
4.8.7 Nintedanib – Boehringer Ingelheim
5 Market Forecast to 2020
5.1 Global Market
5.1.1 Treatment Use Patterns
5.1.2 Market Size
5.2 North America
5.2.1 Treatment Use Patterns
5.2.2 Annual Cost of Therapy
5.2.3 Market Size
5.3 Top Five European Markets
5.3.1 Treatment Use Patterns
5.3.2 Annual Cost of Therapy
5.3.3 Market Size
5.4 Japan
5.4.1 Treatment Use Patterns
5.4.2 Annual Cost of Therapy
5.4.3 Market Size
5.5 Drivers and Barriers for the Colorectal Cancer Therapeutics in Major Developed Markets to 2020
5.5.1 Drivers
5.5.2 Barriers
6 Deals and Strategic Consolidations
6.1 Licensing Agreements
6.1.1 Major Licensing Deals
6.2 Co-development Agreements
6.2.1 Major Co-development Agreements
7 Appendix
7.1 All Pipeline Drugs by Phase
7.1.1 Discovery
7.1.2 Preclinical
7.1.3 IND/CTA-Filed
7.1.4 Phase I
7.1.5 Phase II
7.1.6 Phase III
7.2 Market Forecasts to 2020
7.2.1 Global
7.2.2 US
7.2.3 Canada
7.2.4 UK
7.2.5 France
7.2.6 Germany
7.2.7 Italy
7.2.8 Spain
7.2.9 Japan
7.3 Market Definitions
7.4 Abbreviations
7.5 References
7.6 Research Methodology
7.6.1 Coverage
7.6.2 Secondary Research
7.6.3 Primary Research
7.6.4 Therapeutic Landscape
7.6.5 Geographical Landscape
7.6.6 Pipeline Analysis
7.7 Expert Panel Validation
7.8 Contact Us
7.9 Disclaimer
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